Role of Pro-Anthocyanidin in Gynecomastia and Related Oligospermia and Asthenospermia

A case of 15 years old boy, with gynecomastia, absence of secondary sexual characters, low sperm count and low sperm motility on semen analysis is presented. His hormonal profile was normal for age. The patient was prescribed proanthocyanidin 75 mg dosage twice a day and followed up regularly. In the following 5 years, his gynecomastia improved, secondary sexual characters appeared and sperm count normalized. The case is described for the novel indication of proanthocyanidin in treating gynecomastia, oligo- and asthenospermia in the presence of a normal hormonal profile. Its plausible mode of action is debatable.


Virendra Sehgal N, Naresh Sehgal, Ruchi Sehgal, Deepa Sehgal, and Ananta Khurana

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